3rdInternational Conference and Exhibition on Nutrition & Food Sciences
September 23-25, 2014 Valencia , Spain
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Abstract
Chronic exposure to air pollution particularly ambient fine particulate matter (PM2.5) have been reported to increase cardiovascular mortality and the risk of several chronic diseases (CVD, diabetes, COPD, Cancer.) via oxidative stress an inflammatory mechanisMS. Thus, air pollution is a significant threat to human health worldwide as globally 80% of the population lives in regions that exceed WHO air quality guidelines (AQG). Consumption of a healthy diet is critical to maintain human health. Epidemiological studies have shown that omega-3 PUFA, a Mediterranean diet rich in micronutrients and secondary plant metabolites and an adequate intake of essential micronutrients effectively reduce the risk of cardiovascular diseases and chronic diseases, through anti-oxidative and anti-inflammatory activities.
The presentation will highlight a few nutrients which may support the body against damage induced by particulate matter such as PM2.5. The first intervention studies in human indicate that nutrients such as omega-3 PUFA, antioxidants (vitamin C, E ..) and B vitamin’s may attenuate the damage induced by air pollution. In a recent study vitamin E and C boosted superoxide dismutase (SOD) and glutathione reductase, and normalized glutathione and glutathione peroxide altered by pollution exposure. Intervention studies showed that fish oil attenuated heart rate variability decline caused by air pollution, boosted endogenous antioxidant defense (SOD, GSH) and inhibited lipoperoxidation (LPO).
In the presence of air pollution a healthy nutrition with adequate intake of essential micronutrients is even more critical to avoid a double “hit” that may further promote damage induced by air pollution
Biography
Manfred Eggersdorfer is Senior Vice President for Nutrition Science & Advocacy at DSM Nutritional Products. He studied chemistry at the Technical University Munich and did his PhD in organic chemistry in the field of synthesis and characterization of unusual amino acid. He was post-doc at the Stanford-University, California working with Carl Djerassi on the isolation and characterization of sterols from marine origin. Manfred Eggersdorfer is active as professor for Healthy Ageing at the Faculty of Medical Sciences at the University of Groningen. He is member of the Advisory Board of the Johns Hopkins Bloomberg School of Public Health, of the Fraunhofer-Gesellschaft Curatorial for Innovation, and affiliate of various other organizations. He is author of numerous publications in the fields of vitamins, innovation in nutritional ingredients, and renewable resources, reviewer for a variety of journals and associate editor of the “International Journal of Vitamin and Nutrition Research.
camera iphone 8 plus apk Manfred Eggersdorfer| University Medical Center Groningen and DSM | Nutritional Science 2014 | |
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